BPC-157

Once-daily subcutaneous protocol for tissue-healing and cytoprotective research.

BPC-157

BPC-157 (Body Protection Compound-157) is a synthetic 15 amino acid peptide derived from a gastric protein sequence studied for tissue-healing and cytoprotective properties. Preclinical models demonstrate accelerated wound repair and anti-inflammatory act

Vial Size
Dose Range
Schedule
Primary Goal
10 mg vial 200 to 600 mcg daily with gradual titration. Daily subcutaneous injections for 8 to 12 weeks (extend to 16 weeks if desired). Support tissue-healing and recovery processes based on preclinical evidence.

Reconstitution Summary

1 mL per 10 mg vial (10 mg/mL).

Storage Summary

Lyophilized frozen; reconstituted refrigerated; avoid freeze-thaw.
BPC-157 10mg
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BPC-157 10mg

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Reconstitution Steps

  1. Draw 1 mL bacteriostatic water with a sterile syringe.
  2. Inject slowly down the vial wall; avoid foaming.
  3. Gently swirl until dissolved (do not shake).
  4. Label and refrigerate at 2 to 8 °C, protected from light. At 10 mg/mL, 1 unit = 0.01 mL » 100 mcg on a U-100 insulin syringe.

How It Works

BPC-157 is a synthetic peptide corresponding to a partial sequence of human gastric juice protein. Preclinical studies suggest it modulates nitric oxide pathways and growth-factor expression to promote angiogenesis and collagen deposition in damaged tissues. Animal models report accelerated healing of gut, tendon, ligament, and muscle injuries. A Phase I oral safety trial has been completed, and a small human case series reported improvements following intra-articular administration; however, large-scale controlled human efficacy data are not yet available.

Benefits & Side Effects

  • Supports tissue repair in gut, tendon, muscle, and skin injury models (animal data).
  • Demonstrates anti-inflammatory and cytoprotective properties in preclinical settings.
  • Phase I safety studies report good tolerability with no serious adverse events at tested doses.
  • Occasional mild injection-site reactions (redness, itch) may occur with subcutaneous administration.
  • Long-term human safety and efficacy remain under investigation.

References & Scientific Literature

  1. Sikiric P et al. BPC-157 stable gastric pentadecapeptide: novel therapy for wound healing (Current Pharmaceutical Design).
  2. Seiwerth S et al. BPC-157 and angiogenic growth factors: GI tract healing and beyond (Life Sciences).
  3. Vasireddi N et al. Emerging use of BPC-157 in orthopaedic sports medicine: systematic review (HSS Journal, 2025).
  4. Chang CH et al. BPC-157 promotes tendon-to-bone healing in rat rotator cuff model (Journal of Orthopaedic Research).
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